Error E0009585 Backups of VMs failing

I recently upgraded from Backup Exec 2012 to 2014.  I had a job setup to backup all of my Virtual Machines.  The job used to complete, although it took a very long time.  Now the job fails and I get Error Code E0009585.  In the job log I get V-79-57344-38277 - Unable to open a disk of the virtual machine.  It always fails when it hit a particular server.

I'm not sure why this job is failing, it used to run fine.  I have updated the agents on all the servers after the upgrade.  Any help would be greatly appreciated.

Thanks